Ragweed is my most severe allergy trigger. The pills that I was taking had become ineffective. However, I did not want to go the route of the prescription strength. From the label these seemed to be what I needed for my multiple symptoms. Indeed I did get great relief within an hour. Effectiveness For a store brand allergy relief, I found these to be quite effective. I have to say that the 24 hour label is a bit of a stretch. I did have to take an extra dose when I was outside during ragweed season. However, these pills did treat my multi-symptom issues of itchy eyes, throat and sneezing. Ease of Use The tablets were nicely coated. They are a tad larger than the Chlortabs and Benedryl type tablets. However the coating did help them to go down easily. The 24 hour dosage is a bit of a misnomer. With it being ragweed season I did have to off label dose after being outside all day at work. Immediacy I took the dosage right at the first sign of my itchy throat and nose. Within the hour, my eyes felt better and the sneezing had stopped.